240 research outputs found

    Analysis of a new family of DC-DC converters with input-parallel output-series structure

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    There is an increasing trend of development and installation of switching power supplies due to their highly efficient power conversion, fast power control and high quality power conditioning for applications such as renewable energy integration and energy storage management systems. In most of these applications, high voltage conversion ratio is required. However, basic switching converters have limited voltage conversion ratio. There has been much research into development of high gain power converters. While most of the reported topologies focus on high gain and high efficiency, in this thesis, the input and output ripple currents and reliability are also considered to derive a new converter structure suitable for high step-up voltage conversion applications. High ripple currents and voltages at the input and output of dc-dc converters are not desirable because they may affect the operation of the dc source or the load. A number of converters operating in an interleaved manner can reduce these ripples. This thesis proposes a dc/dc switching converter structure which is capable of reducing the ripple problem through interleaved action, in addition to high gain and high efficiency voltage conversion. The thesis analyses the proposed converter structure through a dual buck-boost converter topology. The structure allows different converter topologies and combinations of them for different applications to be configured. The study begins with a motivation and a literature review of dc/dc converters. The new family of high step-up converters is introduced with an interleaved buck-boost as an example, followed by small-signal analysis. Experimental verifications, conclusions and future work are discussed

    De aquakultuur met benuttiging van bio-industriĂŤle afvalstoffen en thermische effluenten = L'aquaculture utilisant des dechets bio-industriels et des effluents thermiques

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    The possibility of recycling biodegradable waste materials (manure and waste from agricultural crops) into new proteins was investigated through experiments with various aquaticfood chains. The possibility of increasing the biomass yield through recuperation of the lost energy of thermal effluents was continually taken into consideration. The most promising production procedures which could lead to industrial applificatians are: a) the controlled mass production of pickling lobsters (Artemia) in "batch" or "flow through" systems using agricultural wastes, b). the nursery production of edible shell-fish (oysters, Paphia pullastra clams) using microscopic algae which were grown on manure. Units were designed of both types on a semi-industrial scale and were built on the Belgian coast. In conclusion it can also be mentioned that the mass production of water fleas (Daphnia) using manure and agricultural waste gave very encouraging results on a laboratory scale

    Analysis of the DNA adducts of phenyl glycidyl ether in a calf thymus DNA hydrolysate by capillary zone electrophoresis-electrospray mass spectrometry: evidence for phosphate alkylation

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    Calf thymus DNA was reacted irt vitro with phenyl glycidyl ether (PGE) and was hydrolysed enzymatically, to the 5'-monophosphate nucleotides using deoxyribonuclease I (DNA-ase I) and nuclease P1, The adducts were concentrated using solid phase extraction (SPE), on a polystyrene divinylbenzene copolymer in order to remove the unmodified nucleotides. The adducts could be identified using capillary zone electrophoresis-electrospray tandem mass spectrometry (CZE ES-MS/MS), using sample stacking. In addition to the base alkylated 2'-deoxynucleotides present in the DNA-hydrolysate, also phosphate alkylated 2'-deoxynucleotide adducts were identified for TMP and dAMP, An additional adduct, dUMP alkylated on the uridine moiety was found originating from the hydrolytic deamination of dCMP alkylated on N-3 Of the cytosine moiety, Enzymatic hydrolysis using nuclease P1 was incomplete as shown by the presence of dinucleotides alkylated on the base moiety, They were successfully hydrolysed to the corresponding 2'-deoxynucleotides by snake venom phosphodiesterase (SVP), Data are shown indicating that alkylations on the pyrimidine bases were more resistant to enzymatic hydrolysis with nuclease P1 than the purine alkylated products

    Energy efficiency considerations in integrated IT and optical network resilient infrastructures

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    The European Integrated Project GEYSERS - Generalised Architecture for Dynamic Infrastructure Services - is concentrating on infrastructures incorporating integrated optical network and IT resources in support of the Future Internet with special emphasis on cloud computing. More specifically GEYSERS proposes the concept of Virtual Infrastructures over one or more interconnected Physical Infrastructures comprising both network and IT resources. Taking into consideration the energy consumption levels associated with the ICT today and the expansion of the Internet in size and complexity, that incurring increased energy consumption of both IT and network resources, energy efficient infrastructure design becomes critical. To address this need, in the framework of GEYSERS, we propose energy efficient design of infrastructures incorporating integrated optical network and IT resources, supporting resilient end-to-end services. Our modeling results quantify significant energy savings of the proposed solution by jointly optimizing the allocation of both network and IT resources

    Research Report 2008–2009

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    The NHMRC Clinical Trials Centre at the University of Sydney runs large multicentre investigator-initiated clinical trials, takes part in trials of national and international collaborative trial groups and contributes expertise to trials run by others. It also: • undertakes research into trial methods and is recognised through publications as a leader in trial methodology • reviews and synthesises evidence from completed trials, and is at the forefront of developments in methods, such as prospective meta-analysis • advises on trial design and operation, and randomises patients and analyses data for other groups conducting trials, particularly through its Outreach program • takes a lead in proposing new directions for trial research in Australia, particularly with regard to integrating clinical trials with national policy and clinical practice • offers placements for postgraduate students in all of these areas • runs short courses in the design and conduct of clinical trials as part of its undertaking to train people for Australian medical research. Core funding is provided by the NHMRC, and specific projects are funded by government, public and private institutions and the pharmaceutical industry. The CTC is at two sites in Camperdown in inner Sydney — the Medical Foundation Building on Parramatta Road and on Mallett Street. This report covers the CTC’s achievements for the biennium 2008–200

    Global stability of enzymatic chain of full reversible Michaelis-Menten reactions

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    International audienceWe consider a chain of metabolic reactions catalyzed by enzymes, of reversible Michaelis-Menten type with full dynamics, i.e. not reduced with any quasi- steady state approximations. We study the corresponding dynamical system and show its global stability if the equilibrium exists. If the system is open, the equilibrium may not exist. The main tool is monotone systems theory. Finally we study the implications of these results for the study of coupled genetic-metabolic systems

    A characteristics framework for Semantic Information Systems Standards

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    Semantic Information Systems (IS) Standards play a critical role in the development of the networked economy. While their importance is undoubted by all stakeholders—such as businesses, policy makers, researchers, developers—the current state of research leaves a number of questions unaddressed. Terminological confusion exists around the notions of “business semantics”, “business-to-business interoperability”, and “interoperability standards” amongst others. And, moreover, a comprehensive understanding about the characteristics of Semantic IS Standards is missing. The paper addresses this gap in literature by developing a characteristics framework for Semantic IS Standards. Two case studies are used to check the applicability of the framework in a “real-life” context. The framework lays the foundation for future research in an important field of the IS discipline and supports practitioners in their efforts to analyze, compare, and evaluate Semantic IS Standard

    A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone

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    Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These recommendations have paved the way for the measurement of nitric oxide to become a diagnostic tool for specific clinical applications. It would be desirable to develop similar guidelines for the sampling of other trace gases in exhaled breath, especially volatile organic compounds (VOCs) which reflect ongoing metabolism. The concentrations of water-soluble, blood-borne substances in exhaled breath are influenced by: (i) breathing patterns affecting gas exchange in the conducting airways; (ii) the concentrations in the tracheo-bronchial lining fluid; (iii) the alveolar and systemic concentrations of the compound. The classical Farhi equation takes only the alveolar concentrations into account. Real-time measurements of acetone in end-tidal breath under an ergometer challenge show characteristics which cannot be explained within the Farhi setting. Here we develop a compartment model that reliably captures these profiles and is capable of relating breath to the systemic concentrations of acetone. By comparison with experimental data it is inferred that the major part of variability in breath acetone concentrations (e.g., in response to moderate exercise or altered breathing patterns) can be attributed to airway gas exchange, with minimal changes of the underlying blood and tissue concentrations. Moreover, it is deduced that measured end-tidal breath concentrations of acetone determined during resting conditions and free breathing will be rather poor indicators for endogenous levels. Particularly, the current formulation includes the classical Farhi and the Scheid series inhomogeneity model as special limiting cases.Comment: 38 page
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